On January 15th 1838, an Army/Navy force entered the Loxahatchee River near Jupiter Inlet and fell into an ambush while approaching a Seminole / Miccosukee village. Because of this skirmish, General Jesup brings a large force down, and on January 24th was the Battle of Loxahatchee. There was heavy fighting and General Jesup is injured in the battle.
The Loxahatchee River at Jonathan Dickinson State Park
Jesus had a similar situation that happened at the first battle of Withlacoochee, where he led the charge into the river and found that the state volunteer soldiers do not follow behind him. It was at that point that he was hit in the face by a musket ball.
General Thomas Sidney Jesup
There are a lot of misconceptions about battles of the 2nd Seminole War, even by those who should know better. Some people say the Battle of Okeechobee was the last large battle of the war. Maybe the last one of that size, but the Battle of Loxahatchee was certainly a large battle too. And there were a few large skirmishes the next four years of the war. Most of what is talked about the war only covers the first half, and never much is said about the second half, although I would consider the second half even bloodier than the first, even if there were mainly smaller skirmishes.
A very fanciful depiction of the Battle of Okeechobee
Another thing I don't know if anyone has considered; I think Loxahatchee may have been the last battle until the end of the war in 1841/42 that had the commander of forces in Florida participating. General Clinch and Governor Call had the battles on the Withlacoochee that the participated in, early in the war. Yes General Taylor was at Okeechobee, but he did not become commander of forces in Florida until the following year. And I can't think of any battles General Armistead was active at. Colonel Worth at the end of the war was actually at the last battle near Lake Apopka in April 1842. So there are four years of the war where battles are fought involving commanders who are lower ranking officers, and this is because the forces involved are smaller.
The war after this point almost became a war of attrition.